| Test Name: | NT-Pro B-type Natriuretic Peptide (Pro-BNP) |
| Epic Order Code: | LAB5099 | | |
| CPT Code: | 83880 | | |
| Specimen(s) Type: | Plasma or Serum; 0.5 mL |
| Acceptable Container(s): |   Tops are light green and gold. |
| Testing Schedule: | 24 hrs/day, 7 days/week |
| Turn Around Time: | STAT: 1 hour | | |
| | Routine: 2 hours | | |
| Collection Information: | No special patient preparation is required. Collect specimens by standard phlebotomy procedures. |
| Transport Information: | Deliver to lab immediately. All specimens must be signed into the laboratory. |
| Reference Clients: | If unable to deliver to the lab within 1 hour, centrifuge the specimen and remove plasma/serum from the red cells. Store and transport at 2-8° C. Specimen must be received in the lab within 24 hours. |
| Causes for Rejection: | Improperly labeled, incorrect container, contaminated, insufficient quantity, incorrect/delay in transport. |
| Reference Range: | 12 - 150 pg/ml |
| Additional Information: | Manufacturer Suggested Rule-out Cutpoints (99% sensitivity, 100% negative predictive value*): |
| | Age <75: | 125 pg/mL | |
| | Age > or 75: | 450 pg/mL | |
| | *Januzzi, et al, found similar results using a single age-independent exclusionary cutpoint of 300 pg/mL. |